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Scientists discover Key Element of Strong Antibody response to COVID-19

Many anti-SARS-CoV-2 antibodies are produced by a common antibody gene. X-ray crystallography revealed how specific features of these antibodies (two of which are depicted here in yellow and orange, attached to the virus) enable potent recognition of the virus’s spike protein. Graphic by Meng Yuan, Hejun Liu and Nicholas Wu in the Wilson lab.

The findings support many vaccine strategies being used to tackle the new coronavirus. A team led by scientists at Scripps Research has discovered a common molecular feature found in many of the human antibodies that neutralize SARS-CoV-2, the coronavirus that causes COVID-19.

The scientists, whose study appears July 13 in Science, reviewed data on nearly 300 anti-SARS-CoV-2 antibodies that their labs and others have found in convalescent COVID...

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