IL-1Ra tagged posts

New Drug Limits and then Repairs Brain Damage in Stroke

Reparative Effects of Interleukin-1 Receptor Antagonist in Young And Aged/Co-Morbid Rodents After Cerebral Ischemia. Brain, Behavior, and Immunity, 2016; DOI: 10.1016/j.bbi.2016.11.013

Reparative Effects of Interleukin-1 Receptor Antagonist in Young And Aged/Co-Morbid Rodents After Cerebral Ischemia. Brain, Behavior, and Immunity, 2016; DOI: 10.1016/j.bbi.2016.11.013

A potential new drug reduces the number of brain cells destroyed by stroke and then helps to repair the damage. A reduction in blood flow to the brain caused by stroke is a major cause of death and disability, and there are few effective treatments. A team of scientists at The University of Manchester has now found that a potential new stroke drug not only works in rodents by limiting the death of existing brain cells but also by promoting neurogenesis.

This finding provides further support for the development of this anti-inflammatory drug, interleukin-1 receptor antagonist (IL-1Ra in short), as a new treat...

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