IL-23 tagged posts

Putting the Brakes on Chronic Inflammation

Gregory Sonnenberg IBD
An overactive immune response can result in autoimmune diseases including inflammatory bowel disease, psoriasis, rheumatoid arthritis and multiple sclerosis. Credit: Ella Marushchenko and Kate Zvorykina (Ella Maru Studio)

Scientists at Weill Cornell Medicine discovered a previously unknown link between two key pathways that regulate the immune system in mammals — a finding that impacts our understanding of chronic inflammatory bowel diseases (IBD). This family of disorders severely impacts the health and quality of life of more than 2 million people in the United States.

The immune system has many pathways to protect the body from infection, but sometimes an overactive immune response results in autoimmune diseases including IBD, psoriasis, rheumatoid arthritis and multiple scler...

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