Research in mice demonstrates how diet alters a gut microbe molecule that, in turn, prompts immune cells to downregulate inflammation. The study elucidates molecular mechanism behind long-standing belief that diet, microbiota, and immunity influence one another in myriad ways. If affirmed in larger animals and humans, the findings could inform the design of small-molecule drugs that regulate immune response to treat inflammatory conditions.
The cliché “you are what you eat” has been used for hundreds of years to illustrate the link between diet and health. Now, an international team of researchers has found the molecular proof of this concept, demonstrating how diet ultimately affects immunity through the gut microbiome.
The work, conducte...
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