ILC3 immune cells tagged posts

Gut reaction: How Immunity ramps up against Incoming Threats

Image result for VIP directly regulates IL-22 production by ILC3s.
ILC2 and ILC3 activities oscillate during the active and resting phase at steady state in wild-type mice.

A new study has revealed how the gut’s protective mechanisms ramp up significantly with food intake, and at times of the day when mealtimes are anticipated based on regular eating habits.

Researchers from the Walter and Eliza Hall Institute found, in laboratory models, that eating sets off a hormonal ‘chain reaction’ in the gut.

Eating causes a hormone called VIP to kickstart the activity of immune cells in response to potentially incoming pathogens or ‘bad’ bacteria. The researchers also found that immunity increased at anticipated mealtimes indicating that maintaining regular eating patterns could be more important than previously thought.

With the rise in conditions a...

Read More