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    immune cells tagged posts

    Study: In patients with Long COVID, Immune cells don’t follow the rules

    January 15, 2024, Categories  Biology/Biotechnology, Health/Medical

    Kailin Yin speaking with Nadia Roan in the lab
    Kailin Yin (left), a postdoctoral fellow in the Roan Lab and co-first author of the study, collaborates with Gladstone Senior Investigator Nadia Roan. Their study revealed unusual activity among certain immune cells in people with long COVID.

    People with long COVID have dysfunctional immune cells that show signs of chronic inflammation and faulty movement into organs, among other unusual activity, according to a new study by scientists at Gladstone Institutes and UC San Francisco (UCSF).

    The team analyzed immune cells and hundreds of different immune molecules in the blood of 43 people with and without long COVID...

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    Drug Triggers Immune Cells to Attack Prostate Cancer

    November 25, 2022, Categories  Biology/Biotechnology, Health/Medical

    A drug compound stimulates immune cells to attack prostate tumors, according to new research from Washington University School of Medicine in St. Louis. Shown is a human prostate cancer organoid, a small 3D structure that serves as a model of prostate tumors. When the organoid is grown with prostate cancer patients’ immune cells, which have been treated with the drug, the immune cells attack the cancer. Red shows dead cells. Blue shows DNA.

    A single drug compound simultaneously attacks hard-to-treat prostate cancer on several fronts, according to a new study in mice and human cells...

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    Nanosecond Pulsed Electric fields activate Immune cells

    August 9, 2019, Categories  Biology/Biotechnology, Health/Medical

    figure3
    Analysis of extracellular DNA by agarose gel electrophoresis. (A) Schematic representation of MNase treatment for liberation of extruded DNA from cells. MNase digests extracellular chromosomal DNA at its linker regions among nucleosomes, leading to the liberation of extracellular chromosomal DNA from their originating cells. Liberated DNA was separated from cells by brief centrifugation and in turn subjected to either DNA purification followed by agarose gel electrophoresis (B) or direct fluorometric measurement with a SYTOX Green dye (Fig. 4). (B) Analysis of MNase-treated extracellular DNA by agarose gel electrophoresis. Differentiated (D) and undifferentiated cells (U) were exposed to the indicated shot numbers of 20 kV/cm nsPEFs...
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    Secret Tunnels Discovered between the Skull and the Brain

    August 29, 2018, Categories  Biology/Biotechnology, Health/Medical

    Newly discovered channels in the skull may provide a shortcut for immune cells going to damaged tissue. Credit: Nahrendorf Lab

    Newly discovered channels in the skull may provide a shortcut for immune cells going to damaged tissue. Credit: Nahrendorf Lab

    Study suggests immune cells rush through channels to get to injured tissue quickly. Bone marrow, the spongy tissue inside most of our bones, produces red blood cells as well as immune cells that help fight off infections and heal injuries. According to a new study of mice and humans, tiny tunnels run from skull bone marrow to the lining of the brain and may provide a direct route for immune cells responding to injuries caused by stroke and other brain disorders. The study was funded in part by the National Institutes of Health and published in Nature Neuroscience.

    “We always thought that immune cells from our arms and legs traveled via blood to damaged brain tissue...

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