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    Immune checkpoint therapy (ICT) tagged posts

    Healthy Gut Bacteria can help Fight Cancer in other parts of the body, researchers find

    March 13, 2023, Categories  Biology/Biotechnology, Health/Medical

    Healthy gut bacteria can help fight cancer in other parts of the body, researchers find
    Immune checkpoint therapy (ICT) helps gut microbiota travel from the gut to the lymph nodes where they activate immune cells (dendritic cells and T cells). Ultimately, both gut microbiota and activated immune cells then enter the tumor. When specific bacteria cannot travel to the lymph node and tumor and activate immune cells, immune checkpoint therapy is not effective. Credit: Science Immunology (2023). DOI: 10.1126/sciimmunol.abo2003

    Researchers at UT Southwestern Medical Center have discovered how healthy bacteria can escape the intestine, travel to lymph nodes and cancerous tumors elsewhere in the body, and boost the effectiveness of certain immunotherapy drugs...

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