immunologic variations tagged posts

Scientists Identify Immunological Profiles of people who make powerful HIV Antibodies

Immune perturbations in HIV-1–infected individuals who make broadly neutralizing_2016-07-30_14-14-25

Comparison of plasma antibody responses. When compared with the A.Control group, the A.bnAb group had higher binding to HIV-1 Env gp120 (A) and gp41 (B) but similar binding (C) to TIV2008. Binding was similar between the B.bnAb and B.Control groups for the same three antigens (D to F). NS, not significant. Each symbol represents data from an individual participant; group medians, range, and quartiles are shown.

Findings provide insight for vaccine development. People living with HIV who naturally produce broadly neutralizing antibodies (bNAbs) that may help suppress the virus have different immunological profiles than people who do not...

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