immunotherapy tagged posts

Immunotherapy Significantly Increases the Number of Patients Free from Bowel Cancer: Clinical trial

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Credit: Unsplash/CC0 Public Domain

An immunotherapy drug given before surgery instead of chemotherapy meant that over ten times more patients with a certain genetic profile were cancer-free after surgery, according to clinical trial results presented by researchers at UCL and UCLH.

The findings, presented at the American Society of Clinical Oncology (ASCO) Annual Meeting 2024, are interim results from the NEOPRISM-CRC phase II clinical trial assessing whether the immunotherapy drug pembrolizumab can improve outcomes for patients with stage two or stage three MMR deficient/MSI-High bowel cancer. The trial was a collaboration among UCL, UCLH, the Christie NHS Foundation Trust in Manchester, St...

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Researchers Develop a New Way to Safely Boost Immune Cells to Fight Cancer

Researchers develop a new way to safely boost immune cells to fight cancer
(Standing, from left) Rong Tong, associate professor in chemical engineering; Wenjun “Rebecca” Cai, associate professor in materials science and engineering; Eungyo Jang; and Ziyu Huo gather around Liqian Niu (seated), who is working with a Luminex 200 machine used to analyze tumor cytokine levels. Credit: Hailey Wade for Virginia Tech.

Last year alone, more than 600,000 people in the United States died from cancer, according to the American Cancer Society. The relentless pursuit of understanding this complex disease has shaped medical progress in developing treatment procedures that are less invasive while still highly effective.

Immunotherapy is on the rise as a possible solution...

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Immunotherapy Eliminates Disease-causing Cells in Mice with MS-like Disease

Successful cancer treatment approach extended to autoimmune disease. Researchers have shown that the cancer therapy known as CAR-T can be applied to multiple sclerosis (MS), an autoimmune disease of the nervous system. The findings extend the powerful tool of immunotherapy to autoimmune diseases, a class of diseases that are often debilitating and difficult to treat.

The cancer therapy known as CAR-T has revolutionized treatment of some blood cancers since it was introduced in 2017. The therapy uses genetically altered immune cells to home in on cancer cells and destroy them.

Now, studying mice with an autoimmune disease similar to multiple sclerosis (MS), researchers at Washington University School of Medicine in St...

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Drug Triggers Immune Cells to Attack Prostate Cancer

A drug compound stimulates immune cells to attack prostate tumors, according to new research from Washington University School of Medicine in St. Louis. Shown is a human prostate cancer organoid, a small 3D structure that serves as a model of prostate tumors. When the organoid is grown with prostate cancer patients’ immune cells, which have been treated with the drug, the immune cells attack the cancer. Red shows dead cells. Blue shows DNA.

A single drug compound simultaneously attacks hard-to-treat prostate cancer on several fronts, according to a new study in mice and human cells...

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