GARA ELIZABETH PHOTOGRAPHYResearchers at Washington University School of Medicine in St. Louis have shown, in a small clinical trial, that pre-activated natural killer cells can help some children and young adults with recurrent AML and few other treatment options. Pictured is Weston Robinett, 3, a patient who received this investigational therapy at Siteman Kids at St. Louis Children’s Hospital and Washington University School of Medicine. He remains in remission more than two years after treatment.
Natural killer cells could help young patients with few treatment options. An immunotherapy harnessing the immune system’s “natural killer” cells has proven effective in treating acute myeloid leukemia (AML) in some adults whose cancers return...
SSRIs and other serotonin blockers cause immune cells to recognize tumor cells again and eliminate them efficiently. (Bild: istock.com/Design Cells)
Classic antidepressants could help improve modern cancer treatments. They slowed the growth of pancreatic and colon cancers in mice, and when combined with immunotherapy, they even stopped the cancer growth long-term. In some cases the tumors disappeared completely, researchers at UZH and USZ have found. Their findings will now be tested in human clinical trials.
Serotonin is a neurotransmitter that is also known as the happiness hormone because of its beneficial effects on mood. In depressed people, the concentration of serotonin in the brain is reduced. The hormone also influences many other functions throughout the body...
Through T cell engineering, researchers at Virginia Commonwealth University Massey Cancer Center show that it’s possible to arrest tumor growth for a variety of cancers and squash the spread of cancer to other tissues. This research will be published in tomorrow’s print edition of Cancer Research.
The paper builds on decades of research by study co-senior author Paul B. Fisher, M.Ph., Ph.D., a member of Massey’s Cancer Biology research program, who discovered a protein called IL-24 that attacks a variety of cancers in several different ways.
In this latest study, Fisher teamed up with his colleague Xiang-Yang (Shawn) Wang, Ph.D...
Sophie Lucas (University of Louvain de Duve Institute) and her team succeeded in neutralising a molecule that blocks the immune system against cancer. UCLouvain scientists discovered that this new immunotherapy increases the action of another well-known but not always effective immunotherapy, and that it makes tumour regression possible. This very promising discovery in the fight against cancer is published in the journal Nature Communications.
Cancer immunotherapy is the manipulation of the immune responses naturally present in the human body to fight cancer. Often, these immune responses are blocked by cells or molecules that prevent them from killing cancer cells, and the tumour is able to establish itself and grow.
In 2004, Sophie Lucas, researcher at the University of Louva...
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