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Molecule that acts on Human Cells might provide hope for ‘Irresistible’ Cold Cure

Small blue blob with yellow innards up against large angular pale green blob with green innards

The molecule (yellow) blocks human NMT (blue), essential for the virus to assemble the capsid ‘shell’ that encloses its RNA genome (green)

Researchers have lab-tested a molecule that can combat the common cold virus by preventing it from hijacking human cells. Early lab-based tests with human cells have shown the molecule’s ability to completely block multiple strains of cold virus, and the team hope to move to animal and then human trials. The results of initial tests are published today in the journal Nature Chemistry.

The common cold is caused by a family of viruses with hundreds of variants, making it nearly impossible to become immune to or vaccinate against all of them. On top of that, the viruses evolve rapidly, meaning they can quickly gain resistance to drugs...

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