indole tagged posts

Children born to mothers who consume a high-fat, high-sugar diet during pregnancy and breastfeeding face a higher risk of developing fatty liver disease later in life.

New research from the University of Oklahoma suggests that risk may be reduced. A recent study has found that supplementing pregnant and lactating mice with a naturally occurring compound produced by healthy gut bacteria significantly lowered rates of fatty liver disease in their offspring as they aged.

The research is published in the journal eBioMedicine.

How gut bacteria compound may help
The compound, called indole, is naturally made by healthy gut bacteria when they break down tryptophan, an amino acid found in foods such as turkey and nuts...

New research shows how indole can reduce inflammation, fatty deposits. A new study led by Texas A&M AgriLife Research scientists shows how a natural compound found in many well-known and widely consumed vegetables can also be used to fight fatty liver disease.

The study demonstrates how non-alcoholic fatty liver disease, or NAFLD, can be controlled by indole, a natural compound found in gut bacteria – and in cruciferous vegetables such as cabbage, kale, cauliflower and Brussels sprouts. It also addresses how this natural compound may lead to new treatments or preventive measures for NAFLD.

The study was recently published in Hepatology...