indole-3-carbinol tagged posts

This is a mouse colon from Cyp1a reporter mice after feeding with I3C.
Credit: Chris Schiering, Francis Crick Institute

Chemicals produced by vegetables such as kale, cabbage and broccoli could help to maintain a healthy gut and prevent colon cancer, a new study from the Francis Crick Institute shows. The research, published in Immunity, shows that mice fed on a diet rich in indole-3-carbinol – which is produced when we digest vegetables from the Brassica genus – were protected from gut inflammation and colon cancer.

While the health benefits of vegetables are well-established, many of the mechanisms behind them remain unknown...