OSKM-Induced XEN Cells Arise during Reprogramming
The stem cell discovery could also offer new ways to study birth defects and other reproductive problems. Tony Parenti, MSU cell and molecular biology graduate student, unearthed the new cells – induced XEN cells, or iXEN – in a cellular trash pile, of sorts. “Other scientists may have seen these cells before, but they were considered to be defective, or cancer-like,” said Parenti. “Rather than ignore these cells that have been mislabeled as waste byproducts, we found gold in the garbage.”
A great deal of stem cell research focuses on new ways to make and use pluripotent stem cells. Pluripotent stem cells can be created by reactivating embryonic genes to “reprogram” mature adult cells...
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