inflammation in multiple sclerosis tagged posts

New insight into the immune signals driving inflammation in multiple sclerosis

New insight into the immune signals driving inflammation in multiple sclerosis
Representative confocal microscopy image of a cross-section of the whole spinal column of an EAE animal co-transferred with control (red) and Tgfbr1-KO (green) cells. Credit: de la Rosa, Kendirli et al

Multiple sclerosis (MS) is a chronic neurological disease characterized by nerve damage and consequent impairments in vision, movement, balance and mental function. In MS, the immune system mistakenly starts attacking myelin, the protective sheath that surrounds axons (i.e., nerve fibers) in the brain, spinal cord and optic nerves.

Macrophages, immune cells responsible for detecting damaged cells, germs or other debris in the central nervous system (CNS) and eliminating them, have been found to play a key role in MS...

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