inflammatory bowel disease tagged posts
The reproduction rates of the bacteria in one’s gut may be a good indicator of health or disease, scientists say. In their examination of human microbiome data, the research group found that particular changes in bacterial growth rates are uniquely associated with type II diabetes; others are tied to inflammatory bowel disease, for example.
The study began w...
Researchers unveil a series of sensors, memory switches, and circuits that can be encoded in the common human gut bacterium. These basic computing elements will allow the bacteria to sense, memorize, and respond to signals in the gut, with future applications that might include the early detection and treatment of inflammatory bowel disease or colon cancer.
Researchers have previously built genetic circuits inside model organisms such as E coli. However, such strains are only found at low levels within the human gut. “We wanted to work with strains like B thetaiotaomicron that are present in many people in abundant levels, and can stably colonize the gut for long periods of time,” Lu says.
METHOD: A series of genetic parts was made th...
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