Inherited retinal degenerations tagged posts

New Hope for Vision Regeneration by Reactivating Dormant Cells in the Retina

New hope for vision regeneration by reactivating dormant cells in the retina
Ikzf1/4 expression induces morphological reprogramming of MG ex vivo. Credit: Proceedings of the National Academy of Sciences (2023). DOI: 10.1073/pnas.2122168120

There’s new hope for potentially restoring vision in patients suffering from degenerative retinal disease, thanks to work by researchers at Université de Montréal.

Published this week in Proceedings of the National Academy of Sciences, the research was led by UdeM medical professor Michel Cayouette, director of cellular neurobiology research at the UdeM-affiliated Montreal Clinical Research Institute.

His research team discovered that cells that lie dormant in the retina (glial cells) can be induced to tansform into cells sharing some properties with cone photoreceptors, which allow people to do things like perceive c...

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