Scientists have found a vulnerability in cancer cells that could make them more susceptible to being destroyed by the immune system, according to a new report in eLife. The discovery could make it possible to circumvent the resistance starting to be seen with a new generation of immunotherapy treatments called checkpoint inhibitors.
Scientists have been heralding immunotherapy treatments as breakthroughs in cancer research as they have prolonged life in some people with previously untreatable cancers. However, not everyone responds to immunotherapy and recent studies suggest that some cancers are able to escape the effects of checkpoint inhibitor drugs...
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