irritable bowel syndrome tagged posts

Targeting a receptor responsible for our sense of touch and temperature, which researchers have now found to be present in our colon, could provide a new avenue for treating chronic pain associated with gastrointestinal disorders such as irritable bowel syndrome.

A team examining the colon, led by Professor Hongzhen Hu at Washington University and Professor Nick Spencer at Flinders University, identified the presence of Piezo2, the subject of the 2021 Nobel Prize in Physiology or Medicine, now known to be responsible for sensing light touch on our skin.

“In discovering that this receptor is also in our gut, there’s the potential that selectively targeting these channels could be used for long-term silencing of pain sensations from internal organs, without the need for frequent c...

KU Leuven researchers have identified the biological mechanism that explains why some people experience abdominal pain when they eat certain foods. The finding paves the way for more efficient treatment of irritable bowel syndrome and other food intolerances. The study, carried out in mice and humans, was published in Nature.

Up to 20% of the world’s population suffers from the irritable bowel syndrome (IBS), which causes stomach pain or severe discomfort after eating. This affects their quality of life...

Differences in gut microbial composition correlate with regional brain volumes in irritable bowel syndrome. Microbiome, 2017; 5 (1) DOI: 10.1186/s40168-017-0260-z

A new study at UCLA has revealed 2 key findings for people with irritable bowel syndrome about the relationship between the microorganisms that live in the gut and the brain. For people with IBS research shows for the first time that there is an association between the gut microbiota and the brain regions involved in the processing of sensory information from their bodies. The results suggest that signals generated by the brain can influence the composition of microbes residing in the intestine and that the chemicals in the gut can shape the human brain’s structure.

Additionally, they gained insight into the connections among chi...

Credit: Martha Sexton/public domain

A team with University of California has found that introducing a type of antimicrobial protein called a microcin into the guts of mice with inflamed bowels caused a reduction in the degree of inflammation. The team describes their study of the use of the protein in mice and their evidence that microcins intercede in the relationship between different types of bacteria in the gut.

Over the past several decades, scientists have made a lot of progress in better understanding the factors that lead to irritable bowel syndrome, IBS, which covers a host of gut ailments, from Crohn’s disease to colitis. Most of them, they believe, are due to harmful gut bacteria multiplying and pushing out beneficial bacteria...