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    Journey from Nucleus to Synapse tagged posts

    Neural Plasticity depends on this long Noncoding RNA’s Journey from Nucleus to Synapse

    April 19, 2021, Categories  Biology/Biotechnology, Health/Medical

    When the brain’s synapses are activated, they set off a signaling cascade that results in the expression of long noncoding RNA called “ADEPTR.” The RNA is quickly transported along dendrites to synapses, where it acts on proteins involved in remodeling. (Image courtesy of Jenna Wingfield and Yibo Zhao of the Puthanveettil lab at Scripps Research)

    Making memories involves more than seeing friends or taking photos. The brain constantly adapts to new information and stores memories by building connections among neurons, called synapses. How neurons do this — reaching out arm-like dendrites to communicate with other neurons — requires a ballet of genes, signaling molecules, cellular scaffolding and protein-building machinery.

    A new study from scientists at Scripps Research and the Max P...

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