Kras gene tagged posts

Amino Acids in Diet could be key to Starving Cancer

The serine synthesis pathway.

Serine and glycine can be taken up by cells through neutral amino acid transporters or synthesized de novo.

Cutting out certain amino acids from the diet of mice slows tumor growth and prolongs survival, according to new research published in Nature. Researchers at the Cancer Research UK Beatson Institute and the University of Glasgow found that removing 2 non-essential amino acids – serine and glycine – from the diet of mice slowed the development of lymphoma and intestinal cancer. The researchers also found that the special diet made some cancer cells more susceptible to chemicals in cells called reactive oxygen species.

Chemotherapy and radiotherapy boost levels of these chemicals in the cells, so this research suggests a specially formulated diet could make conventional cancer treatmen...

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