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A gene linked to unusually long lifespans in humans protects brain stem cells from the harmful effects of stress, according to a new study by Weill Cornell Medicine investigators.

Studies of humans who live longer than 100 years have shown that many share an unusual version of a gene called Forkhead box protein O3 (FOXO3). That discovery led Dr. Jihye Paik, associate professor of pathology and laboratory medicine at Weill Cornell Medicine, and her colleagues to investigate how this gene contributes to brain health during aging.

In 2018, Dr...

Irina M. Bochkis, Ph.D., of the University of Virginia School of Medicine, has made a new discovery that could let us prevent or cure diseases such as diabetes and fatty liver disease — and possibly let us turn back the clock on aging itself. Credit: Dan Addison, University of Virginia Communications

How would we do it? By using viruses as tiny aestheticians. A new discovery about the effects of aging in our cells could allow doctors to cure or prevent diabetes, fatty liver disease and other metabolic diseases – and possibly even turn back the clock on aging itself. The new finding from the University of Virginia School of Medicine suggests that fatty liver disease and other unwanted effects of aging may be the result of our cells’ nuclei getting wrinkly...