leukaemia tagged posts

Breakthrough with cancer vaccine

TRI-based Mater researchers in partnership with The University of Queensland have developed a new cancer vaccine, which has shown promising signs in preclinical laboratory studies.

Scientists have developed a new cancer vaccine with the potential to activate the body’s immune system to fight a range of cancers, including leukaemia, breast cancer, lung cancer and pancreatic cancers.

Scientists are ready to trial a new cancer vaccine in humans following the successful outcome of their preclinical studies.

The new vaccine was developed by a Mater Research team based at The Translational Research Institute in collaboration with The University of Queensland.

Lead Researcher Associate Professor Kristen Radford says the vaccine has the potential to treat a variety of blood cancers ...

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X-ray Crystal Structure Lethal Factor in Stonefish Venom Solved

Stonefish

The stonefish is one of the world’s ugliest and deadliest fish. You’ll know if you step on one; the fish protects itself using 13 razor sharp venom filled spines capable of slicing through reef shoes. The resulting pain is crippling, can last for days and may result in amputation of a limb or death.

Structural Insights of the Stonefish toxin may help combat Transplant Rejection, ie the unexpected insight into a crucial human immune response that is responsible for the failure of up to 30% of bone marrow transplant therapies for treating leukaemia. The knowledge has been used to develop immunosuppressants to improve the success rate of transplant therapies.

The work reveals that the lethal component, a protein, Stonustoxin, is an ancient relative of the human immune protein perforin...

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