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    life span tagged posts

    The Protein CHIP unfurls Anti-Aging activity

    April 21, 2017, Categories  Biology/Biotechnology, Health/Medical

    In a human cell, CHIP (red) is recruited to clusters of a dementia-inducing protein (yellow). There is not enough CHIP for insulin receptor degradation in this situation. The cell undergoes premature aging. (Photo: CECAD)

    In a human cell, CHIP (red) is recruited to clusters of a dementia-inducing protein (yellow). There is not enough CHIP for insulin receptor degradation in this situation. The cell undergoes premature aging. (Photo: CECAD)

    Researchers uncover the link between protein aggregation, aging. Early in evolution, sugar intake and the regulation of life span were linked with each other. The hormone insulin is crucial here. It reduces blood sugar levels by binding to its receptor on the cell surface. However, many processes for stress management and survival are shut down at the same time. When there is a good supply of food, they appear unnecessary to the organism, although this reduces life expectancy over the long term. The insulin receptor thus acts like a brake on life expectancy...

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    Link made between Genetics, Aging

    February 19, 2016, Categories  Biology/Biotechnology, Health/Medical

    Rob Pazdro, left, and Yang Zhou led a study looking at a new pathway by which genetics regulates aging and disease. Credit: Cal Powell/University of Georgia

    Rob Pazdro, left, and Yang Zhou led a study looking at a new pathway by which genetics regulates aging and disease. Credit: Cal Powell/University of Georgia

    Uni of Georgia scientists have shown a hormone instrumental in the aging process is under genetic control, introducing a new pathway by which genetics regulates aging and disease. Previous studies have found that blood levels of this hormone, growth differentiation factor 11, decrease over time. Restoration of GDF11 reverses cardiovascular aging in old mice and leads to muscle and brain rejuvenation, a discovery that was listed as one of the top 10 breakthroughs in science in 2014.

    Scientists in the UGA College of Family and Consumer Sciences have now discovered that levels of this hormone are determined by genetics, representing ano...

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