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This new blood test could detect cancer before it shows up on scans

Caption: When the biomarker is detected, the Cas12a protein used for CRISPR cuts the DNA holding the quantum dots, which causes a measurable drop in SHG signal.
Credit: Han Zhang, Shenzhen University

A new CRISPR-powered light sensor can detect the faintest molecular signs of cancer in a drop of blood. A new light-based sensor can spot incredibly tiny amounts of cancer biomarkers in blood, raising the possibility of earlier and simpler cancer detection. The technology merges DNAnanotechnology, CRISPR, and quantumdots to generate a clear signal from just a few molecules. In lung cancer tests, it worked even in real patient serum samples. Researchers hope it could eventually power portable blood tests for cancer and other diseases.

Scientists have designed a powerful light based sensor...

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