long non-coding RNAs tagged posts

A molecule that suppresses melanoma tumours has been identified. A promising route to develop new treatments for skin cancer has been identified by University of Bath scientists, who have found a molecule that suppresses melanoma tumour growth.

Although the research is at an early stage, the team hope that their work could help develop new ways to combat melanoma and potentially other cancers too.

The team from the University of Bath’s Department of Biology & Biochemistry were researching a group of ‘long non-coding RNAs’ (IncRNAs) with colleagues at the Ludwig Institute for Cancer Research at the University of Oxford, the Wellcome Sanger Institute and University of Lausanne, Switzerland.

IncRNA...

UCLA researchers Tamer Sallam, left, and Peter Tontonoz expect that further exploration will lead to new insights into normal physiology as well as disease.

So-called ‘selfish’ gene acts to remove cholesterol from blood vessels. Scientists have identified a gene that may play a protective role in preventing heart disease. Their research revealed that the gene, called MeXis, acts within key cells inside clogged arteries to help remove excess cholesterol from blood vessels. Published in the journal Nature Medicine, the UCLA-led study in mice found that MeXis controls the expression of a protein that pumps cholesterol out of cells in the artery wall.

MeXis is an example of a “selfish” gene, one that is presumed to have no function because it does not make a protein product...