longevity tagged posts

Study suggests one common amino acid may affect how long men live

Study suggests one common amino acid may affect how long men live

A large new study suggests that higher levels of a common amino acid called tyrosine may be linked to a shorter lifespan in men.

The research, published recently in the journal Aging, examined whether blood levels of two amino acids, phenylalanine and tyrosine, were connected to how long people live.

Amino acids are building blocks of protein. They are found in protein-rich foods such as milk, eggs and meat, and are also sold as dietary supplements.

Researchers from the University of Hong Kong and the University of Georgia analyzed health and genetic data from more than 270,000 people in the U.K. Biobank, a large long-term health study in the U.K.

At first, both amino acids appeared to be tied to a higher risk of death...

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Turning the gut microbiome into a longevity factory

New research finds that low doses of the antibiotic cephalordine induces the cps operon in bacteria, visualized in red. This operon is responsible for synthesizing colanic acids, resulting in attenuation of age-related metabolic changes. Credit: Meng Wang

A team of researchers has found a way to turn the bacteria living in the digestive tracts of animals into factories that can produce compounds that promote longevity in their hosts—showing a potential new drug development strategy.

Janelia Senior Group Leader Meng Wang and her team study longevity and were interested in seeing how they could transfer their research findings about longevity-promoting compounds into practical applications.

One idea they had was to induce the body’s gut microbiota—a collection of bacteria in th...

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Mice Eating Less of Specific Amino Acid – overrepresented in diet of obese people – Live Longer, Healthier

Study: Mice that ate less of an obesity-associated amino acid lived longer, healthier
Credit: Cell Metabolism (2023). DOI: 10.1016/j.cmet.2023.10.005

A new study in mice, published recently in the journal Cell Metabolism, shows that cutting down the amount of a single amino acid called isoleucine can, among other benefits, extend their lifespan, make them leaner and less frail as they age and reduce cancer and prostate problems, all while the mice ate more calories.

There’s a popular saying in some circles that “a calorie is a calorie,” but science shows that it may not be true. In fact, it may be possible to eat more of some kinds of calories while also improving your health.

“We like to say a calorie is not just a calorie,” says Dudley Lamming, a professor and metabolism researcher at the University of Wisconsin School of Medicine and Public Health...

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Cell Protein Discovery points to Healthier Aging

two people with grey hair are walking away from the camera along a sandy track with green vegetation either side
Image: Adobe

Researchers at The University of Queensland have found an anti-ageing function in a protein deep within human cells.

Associate Professor Steven Zuryn and Dr Michael Dai at the Queensland Brain Institute have discovered that a protein called ATSF-1 controls a fine balance between the creation of new mitochondria and the repair of damaged mitochondria.

Mitochondria, with their own DNA, produce energy within cells to power biological functions but the toxic by-products of this process contribute to the rate at which the cell ages.

“In conditions of stress, when mitochondrial DNA has been damaged, the ATSF-1 protein prioritises repair which promotes cellular health and longevity,” Dr Zuryn said.

As an analogy, Dr Zuryn likened the relationship to a race car needing...

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