lung cancer tagged posts

Old Drugs Hint at New Ways to Beat Chronic Pain

Visualizing pain in mouse sensory neurons. Mouse sensory neurons are shown in magenta. BH4, the molecule driving chronic pain, is shown in green. Hence, the neurons “in pain” are seen in green/white. ©Cronin/IMBA

A newly identified link between chronic pain and lung cancer in mice offers hope for pain management. A new study points to possible new treatments for chronic pain with a surprising link to lung cancer. Findings of the research, conducted in laboratory mouse models, open up multiple therapeutic opportunities that could allow the world to improve chronic pain management and eclipse the opioid epidemic.

Pain is an important alarm system that alerts us to tissue damage and prompts us to withdraw from harmful situations...

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How Air Pollution Alters Lung Tissue, increasing Cancer Susceptibility

Inhaled fine particulate matter (shown here in red) pulls strings of collagen to disturb the immune defence in mice with lung cancer cells. This activity delays the movement of cytotoxic T-cells (purple) as they migrate towards the cancer cells (green) to destroy them. Image credit: Wang et al. 

Scientists have identified a mechanism that explains how fine air pollution particles might cause lung cancer, according to a study published today in eLife.

The findings could lead to new approaches for preventing or treating the initial lung changes that lead to the disease.

Tiny, inhalable fine particulate matter (FPM) found in air pollutants has been recognised as a Group 1 carcinogen and a substantial threat to global health...

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Right Program could turn Immune Cells into Cancer Killers

A tumor-specific T cell engages with a tumor cell. Bystander T cells do not engage with the tumor. Credit: PNAS Dec. 10, 2002, Copyright (2002) National Academy of Sciences, U.S.A.

Cancer-fighting immune cells in patients with lung cancer whose tumors do not respond to immunotherapies appear to be running on a different “program” that makes them less effective than immune cells in patients whose cancers respond to these immune treatments, suggests a new study led by researchers at the Johns Hopkins Kimmel Cancer Center Bloomberg~Kimmel Institute for Cancer Immunotherapy.

The findings, published in the August 5 issue of Nature, could lead to new ways to overcome tumor resistance to these treatments.

“Cancer immunotherapies have tremendous promise, but this promise only comes to fr...

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Breakthrough with cancer vaccine

TRI-based Mater researchers in partnership with The University of Queensland have developed a new cancer vaccine, which has shown promising signs in preclinical laboratory studies.

Scientists have developed a new cancer vaccine with the potential to activate the body’s immune system to fight a range of cancers, including leukaemia, breast cancer, lung cancer and pancreatic cancers.

Scientists are ready to trial a new cancer vaccine in humans following the successful outcome of their preclinical studies.

The new vaccine was developed by a Mater Research team based at The Translational Research Institute in collaboration with The University of Queensland.

Lead Researcher Associate Professor Kristen Radford says the vaccine has the potential to treat a variety of blood cancers ...

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