Release of platelets in the lung vasculature. Credit: Image courtesy of University of California – San Francisco
Cells in mouse lungs produce most blood platelets and can replenish blood-making cells in bone marrow, study shows. Using video microscopy in the living mouse lung, UC San Francisco scientists have revealed that the lungs play a previously unrecognized role in blood production. The researchers found that the lungs produced greater than half of the platelets in mouse circulation. In another surprise finding, the scientists also identified a previously unknown pool of blood stem cells capable of restoring blood production when the stem cells of the bone marrow, previously thought to be the principal site of blood production, are depleted.
“This finding definitely suggests a more s...
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