magnesium tagged posts

Researchers from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) have developed a small-molecule drug that prevents weight gain and adverse liver changes in mice fed a high-sugar, high-fat Western diet throughout life.

“When we give this drug to the mice for a short time, they start losing weight. They all become slim,” said Madesh Muniswamy, Ph.D., professor of medicine in the health science center’s Joe R. and Teresa Lozano Long School of Medicine.

Findings by the collaborators, also from the University of Pennsylvania and Cornell University, were published Feb...

The level of magnesium in the blood is an important factor in the immune system’s ability to tackle pathogens and cancer cells. Writing in the journal Cell, researchers from the University of Basel and University Hospital Basel have reported that T cells need a sufficient quantity of magnesium in order to operate efficiently. Their findings may have important implications for cancer patients.

Magnesium deficiency is associated with a variety of diseases, such as infections and cancer...

Possible roles of magnesium in vitamin D synthesis. Magnesium is involved in both activation and inactivation of vitamin D. Abbreviations: 1,25(OH)2D, 1,25-dihydroxyvitamin D (biologically active form); 24,25(OH)2D, 24,25-Dihydroxyvitamin D; 25(OH)D, calciferol (inactive form); D2, vitamin D2 (from nonanimal sources); D3, vitamin D3 (from animal sources); DBP, vitamin D–binding protein; Mg, magnesium; VDR, vitamin D receptors.

Up to 50% of US population is magnesium deficient. Vitamin D can’t be metabolized without sufficient magnesium levels, meaning Vitamin D remains stored and inactive for as many as 50% of Americans. In addition, Vitamin D supplements can increase a person’s calcium and phosphate levels even while they remain Vitamin D deficient...

An essential mineral in our diets has an unexpected role in helping living things remain adapted to the rhythms of night and day. Mg – a nutrient found in many foods – helps control how cells keep their own form of time to cope with the natural environmental cycle of day and night. The discovery in cells is expected to be linked to whole body clocks which influence circadian rhythms – of sleeping and waking, hormone release, body temperature and other important bodily functions in people.

The surprising discovery may aid the development of chronotherapy – Rx scheduled according to time of day – in people, and development of new crop varieties with increased yields or adjustable harvesting seasons...