magnetic nanoparticles tagged posts

Bacteria-based Biohybrid Microrobots on a Mission to one day Battle Cancer

Bacterial biohybrids carrying nanoliposomes (200 nm) and magnetic nanoparticles (100 nm). Nanoliposomes are loaded with chemotherapeutic DOX and photothermal agent ICG, and both cargoes are conjugated to E. coli bacteria (2 to 3 µm in length) via biotin-streptavidin interactions. Akolpoglu et al., Sci. Adv. 8, eabo6163 (2022).

A team of scientists in the Physical Intelligence Department at the Max Planck Institute for Intelligent Systems have combined robotics with biology by equipping Ecoli bacteria with artificial components to construct biohybrid microrobots. First, the team attached several nanoliposomes to each bacterium. On their outer circle, these spherical-shaped carriers enclose a material (ICG, green particles) that melts when illuminated by near infrared light...

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Researchers achieve Remote Control of Hormone Release

MIT engineers have developed magnetic nanoparticles (shown in white squares) that can stimulate the adrenal gland to produce stress hormones such as adrenaline and cortisol.
Image: Courtesy of the researchers

Abnormal levels of stress hormones such as adrenaline and cortisol are linked to a variety of mental health disorders, including depression and posttraumatic stress disorder (PTSD). MIT researchers have now devised a way to remotely control the release of these hormones from the adrenal gland, using magnetic nanoparticles.

This approach could help scientists to learn more about how hormone release influences mental health, and could eventually offer a new way to treat hormone-linked disorders, the researchers say...

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Smart Microrobots that can Adapt to their Surroundings

Scientists at EPFL and ETH Zurich have developed tiny elastic robots that can change shape depending on their surroundings.
Credit: EPFL

One day we may be able to ingest tiny robots that deliver drugs directly to diseased tissue, thanks to research being carried out at EPFL and ETH Zurich. The group of scientists – led by Selman Sakar at EPFL and Bradley Nelson at ETH Zurich – drew inspiration from bacteria to design smart, biocompatible microrobots that are highly flexible. Because these devices are able to swim through fluids and modify their shape when needed, they can pass through narrow blood vessels and intricate systems without compromising on speed or maneuverability...

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Fighting Myocardial Infarction with Nanoparticle Tandems

Via a cannula introduced into the infarction area, the cells loaded with magnetic nanoparticles are injected into the damaged heart muscle tissue of the mouse. Credit: Copyrighted Photo: Dr. Annika Ottersbach/Uni Bonn

Via a cannula introduced into the infarction area, the cells loaded with magnetic nanoparticles are injected into the damaged heart muscle tissue of the mouse. Credit: Copyrighted Photo: Dr. Annika Ottersbach/Uni Bonn

Researchers show in mice that transplanted muscle cells display improved engraftment in a magnetic field How can damaged cardiac tissue following a heart attack best be treated with replacement muscle cells? A team under the supervision of the University of Bonn is now presenting an innovative method on mice: Muscle replacement cells, which are to take over the function of the damaged tissue, are loaded with magnetic nanoparticles...

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