Egress of sperm autoantigen from seminiferous tubules maintains systemic tolerance
Unexpected connection likely sabotaging vaccines designed to treat cancer. The University of Virginia School of Medicine has again shown that a part of the body thought to be disconnected from the immune system actually interacts with it, and that discovery helps explain cases of male infertility, certain autoimmune diseases and even the failure of cancer vaccines. Scientists developing such vaccines may need to reconsider their work in light of the new findings or risk unintentionally sabotaging their own efforts...
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