mast cells tagged posts

First Step in Allergic Reactions, Paving the way for New Preventative Strategies

Scientists at Duke-NUS Medical School have identified how the first domino falls after a person encounters an allergen, such as peanuts, shellfish, pollen or dustmites. Their discovery, published in the April issue of Nature Immunology, could herald the development of drugs to prevent these severe reactions.

It is well established that when mast cells, a type of immune cell, mistake a harmless substance, such as peanuts or dust mites, as a threat, they release an immediate first wave of bioactive chemicals against the perceived threat...

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Scientists reveal mechanism that causes Irritable Bowel Syndrome

Patients with irritable bowel syndrome are not always taken seriously by doctors, says Professor Guy Boeckxstaens. | © Shutterstock

KU Leuven researchers have identified the biological mechanism that explains why some people experience abdominal pain when they eat certain foods. The finding paves the way for more efficient treatment of irritable bowel syndrome and other food intolerances. The study, carried out in mice and humans, was published in Nature.

Up to 20% of the world’s population suffers from the irritable bowel syndrome (IBS), which causes stomach pain or severe discomfort after eating. This affects their quality of life...

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