medical diagnostics tagged posts

Researchers show that the light emitted by a single molecule can be detected with a low-cost optical setup. Their prototype could facilitate medical diagnostics. Biomarkers play a central role in the diagnosis of disease and assessment of its course. Among the markers now in use are genes, proteins, hormones, lipids and other classes of molecules. Biomarkers can be found in the blood, in cerebrospinal fluid, urine and various types of tissues, but most of them have one thing in common: They occur in extremely low concentrations, and are therefore technically challenging to detect and quantify.

Many detection procedures use molecular probes, such as antibodies or short nucleic-acid sequences, which are designed to bind to specific biomarkers...

In a groundbreaking new study, researchers at the University of Minnesota, in collaboration with the U.S. Army Combat Capabilities Development Command Soldier Center, have 3D printed unique fluid channels at the micron scale that could automate production of diagnostics, sensors, and assays used for a variety of medical tests and other applications.

The team is the first to 3D print these structures on a curved surface, providing the initial step for someday printing them directly on the skin for real-time sensin...

This is Francesco Greco, researcher at TU Graz in Austria, with a temporary tattoo electrode. Credit: Lunghammer – TU Graz

Electrodes for longterm monitoring of electrical impulses of heart or muscles in the form of temporary tattoos produced using an ink-jet printer. In the case of diagnostic methods such as electrocardiogram (ECG) and electromyography (EMG), gel electrodes are the preferred method of transmitting electric impulses from the heart or muscle. In clinical practice the frequently stiff and cumbersome electrodes noticeably restrict the mobility of patients and are not very comfortable. Because the gel on the electrodes dries out after a short time, the possibilities of taking measurements over a longer period using this kind of electrode are limited.

In the presented method, c...

Artist’s concept of a stingray soft robot. (Image: UCLA)

UCLA bioengineering professor Ali Khademhosseini has led the development of a tissue-based soft robot that mimics the biomechanics of a stingray. The new technology could lead to advances in bio-inspired robotics, regenerative medicine and medical diagnostics. The simple body design of stingrays, specifically, a flattened body shape and side fins that start at the head and end at the base of their tail, makes them ideal to model bio-electromechanical systems on.

The 10-millimeter long robot is made up of four layers: tissue composed of live heart cells, two distinct types of specialized biomaterials for structural support, and flexible electrodes...