Medulla tagged posts

Dreams Turned Off and On with a Neural Switch

stimulating dream sleep

When a laser triggers an optogenetic switch in neurons in the medulla of a sleeping mouse, the animal goes from non-REM sleep (NREM) into REM or dream sleep. The axons of these neurons (green) reach into distant parts of the primitive brain, such as the hypothalamus, broadly affecting brain function. (Franz Weber image.)

Activating small group of neurons in medulla causes rapid transition to REM sleep. The researchers inserted an optogenetic switch into a group of nerve cells located this area, allowing them to activate or inactivate the neurons with laser light. When the neurons were activated, sleeping mice entered REM sleep within seconds...

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