melanoma tagged posts

Cancer cells don’t live on glass slides, yet the vast majority of images related to cancer biology come from the cells being photographed on flat, 2D surfaces – images sometimes used to make conclusions about the behaviour of cells that normally reside in a more complex environment...

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A new 3-drug delivery system for cancer treatment, especially metastatic melanoma, the deadliest form of skin cancer, has been developed by researchers. The work has demonstrated that the system may have particular value with cancers like this that often spread through the lymphatic system. It may offer a novel therapeutic option for more effective cancer treatment.

The new technology takes advantage of nanoparticles that can migrate to, and increase the effectiveness of an attack on cancer cells in the body’s lymph nodes. This can also reduce the development of drug resistance and the broader toxicity often associated with this type of chemotherapy.

“Melanoma has...

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The results reinforce previous findings that antioxidants hasten the progression of lung cancer. People with cancer or an elevated risk of developing the disease should avoid nutritional supplements that contain antioxidants, the researchers say. Given well-established evidence that free radicals can cause cancer, the research community had simply assumed that antioxidants, which destroy them, provide protection against the disease.

“As opposed to the lung cancer studies, the primary melanoma tumor was not affected,” Professor Bergö says. “But the antioxidant boosted the ability of the tumor cells to metastasize, an even more serious problem because metastasis is the cause of death in the case of melanoma. The primary tumor is not dangerous per se and is usually removed.”

Experiments ...

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