Distribution of the 40 nonsynonymous MT2 variants identified by exon resequencing.
New light has been shed on why people who carry a common genetic melatonin receptor mutation may be more at risk for developing type 2 diabetes. By carefully studying healthy subjects, researchers were able to chart the effect of melatonin supplements on blood sugar control. Their results suggest that taking melatonin close to mealtimes may put people with a common genetic variant more at risk.
As many as 50% of people of European ancestry carry this genetic variation in MTNR1B, a gene that encodes a melatonin receptor...
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