mental flexibility tagged posts

Human CLOCK gene enhances brain connectivity and mental flexibility in mice, study finds

Human CLOCK gene enhances brain connectivity and mental flexibility in mice, study finds
Example images of excitatory neurons from the cerebral cortexes of humanized mice showing how the neurons from the humanized mice grew more dendrites. Credit: Dr. Yuxiang Liu

Clock genes are a set of genes known to contribute to the regulation of the human body’s internal 24-hour cycle, also known as the circadian rhythm. One of these genes is the so-called CLOCK gene, a protein that regulates the activity of other genes, contributing to recurrent patterns of sleep and wakefulness.

Past findings suggest that this gene is also expressed in the neocortex, a brain region that supports important cognitive abilities, including reasoning, decision-making and the processing of language. However, the gene’s possible contribution to these specific brain functions remains poorly understood.

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Creativity and Humor shown to Promote Well-Being in Older Adults via Similar Mechanisms

creative senior
Credit: cottonbro studio from Pexels

Many people associate aging with a decline in cognitive function, health issues, and reduced activity. Uncovering mental processes that can boost the well-being of the older adults could be highly beneficial, as it could help to devise more effective activities aimed at improving their quality of life.

Researchers at University of Brescia and the Catholic University of the Sacred Heart recently carried out a study investigating the contribution of creativity and humor to the well-being of the elderly. Their findings, published in Neuroscience Letters, show that these two distinct human experiences share common psychological and neurobiological processes that promote well-being in older adults.

“Our recent study belongs to a line of research ai...

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