metabolic syndrome tagged posts

A study spearheaded by Oregon State University has shown why certain polyunsaturated fatty acids work to combat a dangerous liver condition, opening a new avenue of drug research for a disease that currently has no FDA-approved medications.

Scientists led by Oregon State’s Natalia Shulzhenko, Andrey Morgun and Donald Jump used a technique known as multi-omic network analysis to identify the mechanism through which dietary omega 3 supplements alleviated nonalcoholic steatohepatitis, usually abbreviated to NASH.

The mechanism involves betacellulin, a protein growth factor that plays multiple positive roles in the body but also contributes to liver fibrosis, or scarring, and the progression to cirrhosis and liver cancer.

“We only succeeded in ...

Metabolic syndrome increases a person’s risk for diabetes, heart disease, and stroke, and includes conditions such as obesity, high blood pressure and high blood sugar...

Intrahepatic IFN-I signaling and responsive CD8+ T cells promote metabolic disease in mice and correlate to worsened NAFLD in humans.

A high-fat diet and obesity turn “hero” virus-fighting liver immune cells “rogue”, leading to insulin resistance, a condition that often results in type 2 diabetes, according to research published today in Science Immunology. Using cells from mice and human livers, Toronto General Hospital Research Institute researchers demonstrated for the first time how under specific conditions, such as obesity, liver CD8+ T cells, white blood cells in the control of viral infections, become highly activated and inflammatory, reprogramming themselves into disease-driving cells.

Scientists have been trying for many years to discover why the liver continues to pump out too ...

Some of pharmacologically active constituents of avocado.

A new review investigates the effects of avocados on different components of metabolic syndrome, which is a clustering of risk factors including high blood sugar, cholesterol, blood pressure, and body mass index. These risk factors lead to an increased risk of type 2 diabetes and cardiovascular disease.

According to studies reported in the literature, avocados have the most beneficial effects on lipid profiles, with changes to LDL-cholesterol, HDL-cholesterol, triglycerides, total cholesterol, and phospholipids. The peel, seed, flesh, and leaves of avocados have differing effects on components of metabolic syndrome.

“Avocado is a well-known source of carotenoids, minerals, phenolics, vitamins, and fatty acids,” wrote the authors of ...