microbes tagged posts

Diet, Microbes and Fat: A new pathway controlling levels of body fat and cholesterol

Diet, microbes and fat: A new pathway controlling levels of body fat and cholesterol
Lipid accumulation in a murine model of fatty liver disease, visualized by color-enhanced lipid droplets (pink) in liver tissue (green). Superimposed chemical structure of a newly discovered bile acid conjugate. Credit: Dr. Mohammad Arifuzzaman, Dr. Christopher Parkhurst, Dr. Frank Schroeder, and Dr. David Artis.

Beneficial gut microbes and the body work together to fine-tune fat metabolism and cholesterol levels, according to a new preclinical study by investigators from Weill Cornell Medicine and the Boyce Thompson Institute at Cornell University’s Ithaca campus.

The research is published in the journal Nature.

The human body has co-evolved with the beneficial microbes that live in the gut (termed the microbiota), resulting in mutually favorable relationships that aid in the d...

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Underground Microbes may have Swarmed Ancient Mars

Underground microbes may have swarmed ancient Mars
This image made available by NASA shows the Jezero Crater area on the planet Mars, captured by the Mars Reconnaissance Orbiter. Ancient Mars may have had an environment capable of harboring an underground world teeming with microscopic organisms. That’s according to French scientists who published their findings, Monday, Oct. 10, 2022. Credit: NASA/JPL-Caltech/USGS via AP, File

Ancient Mars may have had an environment capable of harboring an underground world teeming with microscopic organisms, French scientists reported Monday.

But if they existed, these simple life forms would have altered the atmosphere so profoundly that they triggered a Martian Ice Age and snuffed themselves out, the researchers concluded.

The findings provide a bleak view of the ways of the cosmos...

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Minerology on Mars points to a Cold and Icy Ancient Climate

Researchers expect the volcanoes in Mars' Sisyphi Planum region to look similar to subglacial volcanoes on earth, such as Herðubreið in Iceland. Credit: Purdue University photo/Sheridan Ackiss

Researchers expect the volcanoes in Mars’ Sisyphi Planum region to look similar to subglacial volcanoes on earth, such as Herðubreið in Iceland. Credit: Purdue University photo/Sheridan Ackiss

The climate throughout Mars’ early history has long been debated – was the Red Planet warm and wet, or cold and icy? New research published in Icarus provides evidence for the latter. Mars is littered with valley networks, deltas and lake deposits, meaning it must have had freely flowing water at some point, probably around 4 billion years ago. But climate models of the planet’s deep past haven’t been able to produce warm enough conditions to allow liquid water on the surface.

“There are people trying to model Mars’ ancient climate using the same kind of models we use here on Earth, and they’re hav...

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High-fiber Diet keeps Gut Microbes from eating the Colon’s lining, Protects against Infection, animal study shows

When mice were raised germ-free, then given a transplant of human gut microbes, the impact of fiber on their colons could be seen. Mice fed a high-fiber diet maintained a thick mucus layer along the lining of their colons, while those that received a fiber-free diet saw the mucus layer grow thinner as bacteria capable of digesting mucus proliferated. The thin layer allowed a pathogen bacteria access to the cells of the colon wall. Credit: University of Michigan

When mice were raised germ-free, then given a transplant of human gut microbes, the impact of fiber on their colons could be seen. Mice fed a high-fiber diet maintained a thick mucus layer along the lining of their colons, while those that received a fiber-free diet saw the mucus layer grow thinner as bacteria capable of digesting mucus proliferated. The thin layer allowed a pathogen bacteria access to the cells of the colon wall. Credit: University of Michigan

It sounds like the plot of a 1950s sci-fi movie: normal, helpful bacteria that begin to eat their host from within, because they don’t get what they want. But new research shows that’s exactly what happens when microbes inside the digestive system don’t get the natural fiber that they rely on for food...

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