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“Characterized by insulin resistance, type 2 diabetes is the most prevalent endocrine disease in the world today, responsible for more than $200 billions of healthcare costs annually in the U.S. alone,” says corresponding author Mahtab Jafari, UCI professor of pharmaceutical sciences. “Our findings show Rhodiola rosea might be beneficial for treating this disease and is a good candidate for further investigation.” Steve Zylius / UCI
Botanical extract shows promise as an alternative to drug therapy. A team of researchers led by the University of California, Irvine has discovered that treatment with an extract from the roots of the Rhodiola rosea plant might be effective for helping manage type 2 diabetes, showing promise as a safe and effective non-pharmaceutical alternative.
The type and abundance of bacteria found in the mouth may be linked to lung cancer risk in non-smokers, finds the first study of its kind, published online in the journal Thorax.
Fewer species and high numbers of particular types of bacteria seem to be linked to heightened risk, the findings indicate.
Around one in four cases of lung cancer occurs in non-smokers and known risk factors, such as second hand tobacco smoke, background radon exposure, air pollution, and family history of lung cancer don’t fully explain these figures, say the researchers.
The type and volume of bacteria (microbiome), found in the mouth has been associated with a heightened risk of various cancers including those of the gullet, head and neck, and pancreas.
A metabolite produced following consumption of dietary soy may decrease a key risk factor for dementia — with the help of the right bacteria, according to a new discovery led by researchers at the University of Pittsburgh Graduate School of Public Health.
Their study, published today in the journal Alzheimer’s & Dementia: Translational Research & Clinical Interventions, reports that elderly Japanese men and women who produce equol — a metabolite of dietary soy created by certain types of gut bacteria — display lower levels of white matter lesions within the brain.
“White matter lesions are significant risk factors for cognitive decline, dementia and all-cause mortality,” said lead author Akira Sekikawa, M.D., Ph.D., associate professor of epidemiology at Pitt Public Health...
Microbiome-derived inosine modulates response to checkpoint inhibitor immunotherapy. Science, 2020; eabc3421 DOI
Researchers with the Snyder Institute for Chronic Diseases at the Cumming School of Medicine (CSM) have discovered which gut bacteria help our immune system battle cancerous tumours and how they do it. The discovery may provide a new understanding of why immunotherapy, a treatment for cancer that helps amplify the body’s immune response, works in some cases, but not others. The findings, published in Science, show combining immunotherapy with specific microbial therapy boosts the ability of the immune system to recognize and attack cancer cells in some melanoma, bladder and colorectal cancers.
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