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    microbiome tagged posts

    High levels of Rare Gut Bacteria may be linked to Restless Legs Syndrome

    June 10, 2019, Categories  Uncategorized

    Image result for Restless Leg Syndrome: Does It Start With A Gut Feeling?
    Daniel J Blum, Emmanuel During, Fiona Barwick, Polina Davidenko, Jamie M Zeitzer. 0009 Restless Leg Syndrome: Does It Start With A Gut Feeling? Sleep, 2019; 42 (Supplement_1): A4 DOI: 10.1093/sleep/zsz067.008

    Possible relationship between gut microbial health and sleep disorder. Small intestine bacterial overgrowth (SIBO) may be more prevalent among patients with restless legs syndrome (RLS), according to preliminary findings from a small, new study.

    Results show that SIBO was found in all seven participants who have RLS. In contrast, the prevalence of SIBO in the general population is estimated to be no more than 15%.

    “We’ve observed extremely high rates of small intestinal bacterial overgrowth in the RLS group,” said lead author Daniel Jin Blum, Ph.D., D.B.S.M...

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    Artificial Sweeteners Have Toxic Effects on Gut Bacteria

    October 2, 2018, Categories  Biology/Biotechnology, Health/Medical

    Artificial sweeteners are used in countless food products and soft drinks with reduced sugar content. Many people consume this added ingredient without their knowledge. NeuroscienceNews.com image is in the public domain.

    Artificial sweeteners are used in countless food products and soft drinks with reduced sugar content. Many people consume this added ingredient without their knowledge. NeuroscienceNews.com image is in the public domain.

    FDA-approved artificial sweeteners and sport supplements were found to be toxic to digestive gut microbes, according to a new paper published in Molecules by researchers at Ben-Gurion University of the Negev (BGU) in Israel and Nanyang Technological University in Singapore.

    The collaborative study indicated relative toxicity of six artificial sweeteners (aspartame, sucralose, saccharine, neotame, advantame, and acesulfame potassium-k) and 10 sport supplements containing these artificial sweeteners...

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    Secret to Longevity may Lie in the Microbiome and the Gut

    June 3, 2018, Categories  Biology/Biotechnology, Health/Medical

    Model of mechanisms of gut microbiota-host communication influencing aging factors. The gut microbiota communicates with the metabolic, inflammatory and oxidative stress pathways via direct and indirect mechanisms. As the physiological changes in all three of these axes are cross-regulatory, the simultaneous action implemented by the gut microbiota makes it a powerful influence in aging and age-related chronic disease development. Abbreviations: glucagon-like peptide (GLP)-1, insulin receptor (IR), insulin receptor substrate (IRS)-1, phosphoinositide 3-kinase (PI3K), protein kinase B (Akt), target of rapamycin (TOR), Forkhead Box O protein (FOXO), sterol regulatory element binding protein (SREBP), acetyl CoA carboxylase (ACC), fatty acid synthase (FAS), tight junction proteins (TJPs), lipopolysaccharide (LPS), toll-like receptor (TLR)4, nuclear factor kappa-light-chain enhancer of activated B cells (NF-kB), activator protein (AP)-1, tumor necrosis factor (TNF)-α, interleukin (IL)-6, T helper (Th)17, AMP-activated protein kinase (AMPK), peroxisome proliferator-activated receptor gamma coactivator (PGC)-1α, sirtuin (SIRT), reactive oxygen species (ROS).

    Model of mechanisms of gut microbiota-host communication influencing aging factors. The gut microbiota communicates with the metabolic, inflammatory and oxidative stress pathways via direct and indirect mechanisms. As the physiological changes in all three of these axes are cross-regulatory, the simultaneous action implemented by the gut microbiota makes it a powerful influence in aging and age-related chronic disease development...

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    Mouse study reveals what happens in the Gut after too much Fructose

    February 7, 2018, Categories  Biology/Biotechnology, Health/Medical

    This graphical abstract depicts the findings of Jang et al., which show that it is actually the small intestine that clears most dietary fructose, and this is enhanced by feeding. High fructose doses spill over to the liver and to the colonic microbiota for metabolism.

    This graphical abstract depicts the findings of Jang et al., which show that it is actually the small intestine that clears most dietary fructose, and this is enhanced by feeding. High fructose doses spill over to the liver and to the colonic microbiota for metabolism.

    Princeton University researchers report that in mice, fructose, a sugar found in fruit, is processed mainly in the small intestine, not in the liver as had previously been suspected. Sugary drinks and processed high-sugar foods overwhelm the small intestine and spill into the liver for processing. Additionally, the authors learned that the ability of the small intestine to process fructose is higher after a meal. The work appears February 6 in the journal Cell Metabolism.

    Evidence from previous animal and human studies has s...

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