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    microbiota tagged posts

    Study Reveals Key Role your Gut Bacteria in Body’s Self-Defense

    October 19, 2015, Categories  Biology/Biotechnology, Health/Medical

    Metabolic differences in the small intestine A. Metabolic genes as well as the associated reactions involved in the formation of glutathione (GSH) are presented. B, C Significant differences associated with (B) glycine and (C) glutamine are shown. Red and blue arrows indicate the significantly (Q‐value < 0.05) higher and lower expression of the metabolic genes in CONV‐R mice compared to GF mice, respectively. D. The levels of glycine, glutamine, and cysteine used in the de novo synthesis of the GSH are measured in the hepatic portal vein that conducts blood from the gastrointestinal tract to the liver tissue. *Q‐value < 0.05.

    Metabolic differences in the small intestine A. Metabolic genes as well as the associated reactions involved in the formation of glutathione (GSH) are presented. B, C Significant differences associated with (B) glycine and (C) glutamine are shown. Red and blue arrows indicate the significantly (Q‐value < 0.05) higher and lower expression of the metabolic genes in CONV‐R mice compared to GF mice, respectively. D. The levels of glycine, glutamine, and cysteine used in the de novo synthesis of the GSH are measured in the hepatic portal vein that conducts blood from the gastrointestinal tract to the liver tissue. *Q‐value < 0.05.

    Human intestinal flora regulates the levels of the body’s main antioxidant, glutathione, which fights a host of diseases, new research confirms...

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    Dried plums can reduce risk of colon cancer, research shows

    September 26, 2015, Categories  Biology/Biotechnology, Health/Medical

    Dr. Nancy Turner directed the lab team doing the research on health benefits of dried plums. (Texas A&M AgriLife Research photo)

    Dr. Turner’s lab team, most of who are shown here, were instrumental in the research relating to the health benefits of dried plums. (Texas A&M AgriLife Research photo)

    A diet containing dried plums can positively affect microbiota, also referred to as gut bacteria, throughout the colon, helping reduce the risk of colon cancer, researchers report. According to the American Cancer Society, colon cancer is the third leading cause of cancer-related deaths in the U.S. when men and women are considered separately, and the second-leading cause when the figures are combined. During 2015, colon cancer is expected to cause about 49,700 deaths nationwide.

    “Our research explored the potential cancer-protective properties of dried plums using a well-established rat model of colon cancer,” she sai...

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    How Microbiota Protects against Development of Type 1 Diabetes

    August 7, 2015, Categories  Biology/Biotechnology, Health/Medical

    A pancreatic islet of Langerhans expressing the immunoregulator antimicrobial peptide CRAM (in red). The insulin-producting beta-cells are in green and the glucagon-producting alpha-cells are in blue. Credit: © Julien Diana

    A pancreatic islet of Langerhans expressing the immunoregulator antimicrobial peptide CRAM (in red). The insulin-producting beta-cells are in green and the glucagon-producting alpha-cells are in blue. Credit: © Julien Diana

    A category of antimicrobial peptides, cathelicidins and being researched by a team coordinated by Julien Diana, Inserm Research Fellow at Inserm Unit 1151 is focusing on. Apart from their protective function, these peptides have also exhibited immunoregulatory abilities against several autoimmune diseases.

    They observed that beta pancreatic cells in non-diseased mice produce cathelicidins and that, interestingly, this production is impaired in diabetic mice...

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    How Loss of Bacterial Symbionts Promotes Development of Allergies & acts on Immune System Balance

    July 13, 2015, Categories  Biology/Biotechnology, Health/Medical


      
    The presence of microbes specifically blocks the immune cells responsible for triggering allergies. It is well known the microbiota is involved in many mechanisms, including digestion, vitamin synthesis and host defense.The hygiene hypothesis suggests a link between a decline in infectious diseases and increase in allergic diseases in industrialized countries. Improvements in hygiene levels lead to reduced contact with microbes that is paralleled by an increased incidence in allergic and autoimmune diseases, eg type 1 diabetes.

    Epidemiological studies have substantiated this hypothesis, by showing children living with farm animals – and thus with more microbial agents – develop fewer allergies during their lifetime...

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