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Insight into Brain’s Waste Clearing System may Shed Light on Brain Diseases

focused ultrasound
This microscopic image reveals the enhanced glymphatic transport of an intranasally delivered tracer (red), achieved using ultrasound combined with microbubbles. (Credit: Chen Lab)

Like the lymphatic system in the body, the glymphatic system in the brain clears metabolic waste and distributes nutrients and other important compounds. Impairments in this system may contribute to brain diseases, such as neurodegenerative diseases and stroke.

A team of researchers in the McKelvey School of Engineering at Washington University in St. Louis has found a non-invasive and non-pharmaceutical method to influence glymphatic transport using focused ultrasound, opening the opportunity to use the method to further study brain diseases and brain function...

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