During spaceflight, astronauts lose bone mineral density, but it is not clear exactly what causes this loss. They reared small freshwater fish aboard the International Space Station for 56 days and examined the animals’ jawbones and teeth for any effects from microgravity. Previous studies suggest that microgravity activates osteoclasts, cells that control the breakdown of bone tissue, and the Medaka fish investigation examined the relationship between this increased osteoclast activity and reduced bone mineral density.
Investigators found ...
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