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    mini-brain model tagged posts

    Mini-brain model of Idiopathic Autism reveals underlying Pathology of Neuronal Overgrowth

    July 13, 2016, Categories  Biology/Biotechnology, Health/Medical

    This image shows induced pluripotent stem cell-derived neural progenitor cells after neuronal differentiation. The neurons express a pan neuronal marker Map2 in green and a percentage of the cells express a marker for inhibitory neurons, GABA, in red. The cells' nuclei are stained blue. Credit: UC San Diego Health

    This image shows induced pluripotent stem cell-derived neural progenitor cells after neuronal differentiation. The neurons express a pan neuronal marker Map2 in green and a percentage of the cells express a marker for inhibitory neurons, GABA, in red. The cells’ nuclei are stained blue. Credit: UC San Diego Health

    The vast majority of cases of ASD are idiopathic (cause unknown). Researchers have created a “mini-brain” model, derived from persons with a particular form of idiopathic ASD characterized by over-sized brains, revealing a defective molecular pathway during brain development that results in early neuronal overgrowth and dysfunctional cortical networks...

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