mitochondria of neuron tagged posts

Researchers uncover Where and Why Proteins Malfunction in Parkinson’s disease

Super resolution image of α-synuclein in mitochondria of neuron (left) and single molecule TIRF image of individual α-synuclein aggregates (right)
Super resolution image of α-synuclein in mitochondria of neuron (left) and single molecule TIRF image of individual α-synuclein aggregates (right).
– Mathew Horrocks

Scientists at the Francis Crick Institute, UCL and the University of Edinburgh have uncovered how a build-up of harmful protein starts to happen within neurons in Parkinson’s disease, ultimately causing nerve cell death. By looking at how, where and why this build-up happens, the work provides unique insight into a key biological process driving Parkinson’s.

Parkinson’s is a progressive neurodegenerative disease that causes tremors, slowing of movements, stiffness and can progress to cause severe cognitive problems...

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