mitochondrial alterations tagged posts

Potential Biomarker for Pre-Diabetes discovered that could help Prevent DMII development

 

The Virginia Tech researchers discovered that pre-diabetic people who were considered to be insulin resistant – also had altered mitochondrial DNA. Researchers made the connection by analyzing blood samples taken from 40 participants enrolled in the diaBEAT-it program, a long-term study run by multiple researchers in the Fralin Translational Obesity Research Center and funded by a grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Participants did not have diabetes or cardiovascular disease, but were pre-diabetic and showed signs of insulin resistance.

Blood samples revealed participants had lower amounts of mitochondrial DNA with a higher amount of methylation – a process that can change the expression of genes and mitochondrial copy numbers in ...

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