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Training downregulates acetyl-CoA-generatingpathways in the liver of high-energy diet-fed mice. Abundance of transcripts (gray/blue filled bars) and proteins (blank bars) related to glucose/fructose degradation, mitochondrial pyruvate metabolism, acetyl-CoA conversion and fatty acid synthesis. The mean ± SD values for n = 6–8 are shown. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001, ∗∗∗∗p < 0.0001 for diet, training or interaction by two-way ANOVA as indicated. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001, ∗∗∗∗p < 0.0001 for diet, #p < 0.05, ##p < 0.01 for training by Tukey HSD multiple comparisons test. CON = control diet, HED = high-energy diet, SED = sedentary, TRAIN = treadmill training.
Exercise not only trains the muscles but can also prevent the develop...
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