Zebrafish embryos expressing a fluorescent gene after ultraviolet light irradiation.
A researcher has successfully developed a method to accurately manipulate gene expression by light illumination and demonstrated its usability by creating double-headed zebrafish. It has been difficult to freely manipulate the timing and duration of gene expression using existing gene manipulation technologies, which depend on organism’s gene regulating mechanism. In recent years, methods using light to regulate gene expression have been developed, but deemed insufficient to manipulate embryonic 3development. This is due to a time lag of several hours that occurs from light irradiation to the start/cessation of protein production...
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