mRNA tagged posts

Nanowire Device to Detect Cancer with a Urine Test

Comparison of microRNA extraction using nanowires versus conventional collection (a) Scatterplot comparing normalized intensities of microRNAs extracted with the nanowire device versus conventional collection by ultracentrifugation. (b) Histogram showing the frequency of microRNA species at different fluorescent intensities collected by nanowires (red) and ultracentrifugation (blue). Both the scatterplot and histogram analyses show a notably greater abundance of extracted microRNAs using the nanowire technology. © Takao Yasui

Comparison of microRNA extraction using nanowires versus conventional collection (a) Scatterplot comparing normalized intensities of microRNAs extracted with the nanowire device versus conventional collection by ultracentrifugation. (b) Histogram showing the frequency of microRNA species at different fluorescent intensities collected by nanowires (red) and ultracentrifugation (blue). Both the scatterplot and histogram analyses show a notably greater abundance of extracted microRNAs using the nanowire technology. © Takao Yasui

Cells communicate with each other through a number of different mechanisms...

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Manipulating Gene Expression precisely using Light

Zebrafish embryos expressing a fluorescent gene after ultraviolet light irradiation.

Zebrafish embryos expressing a fluorescent gene after ultraviolet light irradiation.

A researcher has successfully developed a method to accurately manipulate gene expression by light illumination and demonstrated its usability by creating double-headed zebrafish. It has been difficult to freely manipulate the timing and duration of gene expression using existing gene manipulation technologies, which depend on organism’s gene regulating mechanism. In recent years, methods using light to regulate gene expression have been developed, but deemed insufficient to manipulate embryonic 3development. This is due to a time lag of several hours that occurs from light irradiation to the start/cessation of protein production...

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